| 存储条件 |
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| Product Name | CSF1R [B9-B9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C FMS antibody CD 115 antibody CD115 antibody CD115 antigen antibody CFMS antibody Colony stimulating factor 1 receptor antibody Colony stimulating factor I receptor antibody CSF 1 R antibody CSF 1R antibody CSF-1 receptor antibody CSF-1-R antibody CSF1 R antibody CSF1R antibody CSF1R_HUMAN antibody CSFR antibody EC 2.7.10.1 antibody FIM 2 antibody FIM2 antibody FMS antibody FMS proto oncogene antibody FMS protooncogene antibody HDLS antibody M-CSF Receptor antibody M-CSF-R antibody Macrophage colony stimulating factor 1 receptor antibody Macrophage colony stimulating factor I receptor antibody Macrophage colony-stimulating factor 1 receptor antibody McDonough feline sarcoma viral (v fms) oncogene homolog antibody MCSFR antibody Oncogen FMS antibody Proto-oncogene c-Fms antibody V-FMS McDonough feline sarcoma viral oncogen homolog, formerly antibody |
| Product description | c-Fms/CSF-1R, also designated macrophage colony-stimulating factor receptor (M-CSFR), FIM2 or CD115, is a transmembrane tyrosine kinase receptor belonging to the CSF1/PDGF receptor family. It is encoded by the c-Fms proto-oncogene and is expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells and some myoblasts. It is important for growth and differentiation of myeloid cells and its function can be regulated by SLAP-2. c-Fms/CSF-1R is responsible for mediating all of the functions of M-CSF. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB:1:500-1:2,000 ICC:1:100-1:200 IHC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | C FMS antibody CD 115 antibody CD115 antibody CD115 antigen antibody CFMS antibody Colony stimulating factor 1 receptor antibody Colony stimulating factor I receptor antibody CSF 1 R antibody CSF 1R antibody CSF-1 receptor antibody CSF-1-R antibody CSF1 R antibody CSF1R antibody CSF1R_HUMAN antibody CSFR antibody EC 2.7.10.1 antibody FIM 2 antibody FIM2 antibody FMS antibody FMS proto oncogene antibody FMS protooncogene antibody HDLS antibody M-CSF Receptor antibody M-CSF-R antibody Macrophage colony stimulating factor 1 receptor antibody Macrophage colony stimulating factor I receptor antibody Macrophage colony-stimulating factor 1 receptor antibody McDonough feline sarcoma viral (v fms) oncogene homolog antibody MCSFR antibody Oncogen FMS antibody Proto-oncogene c-Fms antibody V-FMS McDonough feline sarcoma viral oncogen homolog formerly antibody |
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| Molecular Weight(MW) | 108 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | P07333 |
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Application
Fig1: Western blot analysis of CSF1R on human CSF1R recombinant protein using anti-CSF1R antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of CSF1R on HEK293 (1) and CSF1R-hIgGFc transfected HEK293 (2) cell lysate using anti-CSF1R antibody at 1/1,000 dilution.
Application
Fig3: ICC staining CSF1R (green) in HepG2 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-CSF1R antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human esophageal tissue using anti-CSF1R antibody. Counter stained with hematoxylin.| Positive Control | Human CSF1R recombinant protein, CSF1R-hIgGFc transfected HEK293 cell lysate, HepG2, human pancreas tissue, human esophageal tissue. |
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| Application Notes | WB:1:500-1:2,000 ICC:1:100-1:200 IHC:1:100-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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