| 存储条件 |
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| Product Name | SERPINA7 [E9-B11] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody Serpin A7 antibody Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody Serpin peptidase inhibitor, clade A, member 7 antibody Serpina7 antibody T4 binding globulin antibody TBG antibody TBG, serum antibody THBG_HUMAN antibody Thyroxin binding globulin antibody Thyroxine binding globulin antibody Thyroxine-binding globulin antibody Thyroxine-binding globulin od serum antibody |
| Product description | There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHCFC |
| WB:1:500-1:2,000 ICC:1:100-1:200 IHC:1:100-1:200 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody Serpin A7 antibody Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 7 antibody Serpin peptidase inhibitor clade A member 7 antibody Serpina7 antibody T4 binding globulin antibody TBG antibody TBG serum antibody THBG_HUMAN antibody Thyroxin binding globulin antibody Thyroxine binding globulin antibody Thyroxine-binding globulin antibody Thyroxine-binding globulin od serum antibody |
|---|---|
| Molecular Weight(MW) | 46 kDa |
| Cellular Localization | Secreted. |
| SwissProt ID | P05543 |
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Application
Fig1: Western blot analysis of SERPINA7 on human SERPINA7 recombinant protein using anti-SERPINA7 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of SERPINA7 on HEK293 (1) and SERPINA7-hIgGFc transfected HEK293 (2) cell lysate using anti-SERPINA7 antibody at 1/1,000 dilution.
Application
Fig3: ICC staining SERPINA7 (green) in A431 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-SERPINA7 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-SERPINA7 antibody. Counter stained with hematoxylin.
Application
Fig6: Flow cytometric analysis of A431 cells with SERPINA7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human SERPINA7 recombinant protein, SERPINA7-hIgGFc transfected HEK293 cell lysate, human liver cancer tissue, human bladder cancer tissue, A431. |
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| Application Notes | WB:1:500-1:2,000 ICC:1:100-1:200 IHC:1:100-1:200 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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