| 存储条件 |
|---|
| Product Name | KDM6A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody bA386N14.2 antibody bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody DKFZp686A03225 antibody Histone demethylase UTX antibody KABUK2 antibody Kdm6a antibody KDM6A_HUMAN antibody Lysine (K) specific demethylase 6A antibody Lysine K specific demethylase 6A antibody Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome antibody Lysine-specific demethylase 6A antibody MGC141941 antibody Ubiquitously transcribed tetratricopeptide repeat X chromosome antibody Ubiquitously transcribed tetratricopeptide repeat protein X linked antibody Ubiquitously transcribed TPR gene on the X chromosome antibody Ubiquitously transcribed TPR protein on the X chromosome antibody Ubiquitously transcribed X chromosome tetratricopeptide repeat protein antibody Ubiquitously-transcribed TPR protein on the X chromosome antibody Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein antibody UTX antibody |
| Product description | Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code . Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' . Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A . |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:100-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX) antibody bA386N14.2 antibody bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX antibody DKFZp686A03225 antibody Histone demethylase UTX antibody KABUK2 antibody Kdm6a antibody KDM6A_HUMAN antibody Lysine (K) specific demethylase 6A antibody Lysine K specific demethylase 6A antibody Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome antibody Lysine-specific demethylase 6A antibody MGC141941 antibody Ubiquitously transcribed tetratricopeptide repeat X chromosome antibody Ubiquitously transcribed tetratricopeptide repeat protein X linked antibody Ubiquitously transcribed TPR gene on the X chromosome antibody Ubiquitously transcribed TPR protein on the X chromosome antibody Ubiquitously transcribed X chromosome tetratricopeptide repeat protein antibody Ubiquitously-transcribed TPR protein on the X chromosome antibody Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein antibody UTX antibody |
|---|---|
| Molecular Weight(MW) | 154 kDa |
| Cellular Localization | Nucleus. |
| SwissProt ID | O15550 |
|---|
Application
Fig1: Western blot analysis of KDM6A on human KDM6A recombinant protein using anti-KDM6Aantibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of KDM6A on HEK293 (1) and KDM6A-hIgGFc transfected HEK293 (2) cell lysate using anti-KDM6A antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with KDM6A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human KDM6A recombinant protein, KDM6A-hIgGFc transfected HEK293 cell lysate, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:100-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
