Brain protein 4.1 antibody SYN 1 antibody SYN 1a antibody SYN 1b antibody SYN I antibody SYN1 antibody SYN1_HUMAN antibody SYN1a antibody SYN1b antibody Synapsin 1 antibody Synapsin I antibody Synapsin-1 antibody Synapsin1 antibody SynapsinI antibody SYNI antibody
Product description
Synapsins are synaptic vesicle-associated phosphoproteins that regulate synaptic vesicle exocytosis and may be involved in synaptogenesis. Evidence suggests that Synapsin I, Synapsin II and Synapsin IIIa are ATP-binding proteins that are regulated by Ca2+ and calmodulin binding. Ca2+ has been shown to stimulate ATP binding to Synapsin I, to have no effect on Synapsin II and to inhibit Synapsin III. Synapsin I and Synapsin II both undergo alternative splicing to produce two forms of each protein, Synapsin la and lb and Synapsin IIa and IIb, respectively. Synapsin III gives rise to at least three isoforms: Synapsin IIIa, IIIb and IIIc. Synapsin III plays unique roles both in early axon outgrowth and in the regulation of synaptic vesicle trafficking. In cultured mouse hippocampal neurons, Synapsin III is expressed early during development, with levels peaking seven days after plating and declining thereafter. Synapsin III is highly concentrated in growth cones.
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser9 of human SynapsinⅠ
Modification
p-S9
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIHC
WB:1:1,000 IHC:1:50-1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Unpurified
Target Information
Alternative Names
Brain protein 4.1 antibody SYN 1 antibody SYN 1a antibody SYN 1b antibody SYN I antibody SYN1 antibody SYN1_HUMAN antibody SYN1a antibody SYN1b antibody Synapsin 1 antibody Synapsin I antibody Synapsin-1 antibody Synapsin1 antibody SynapsinI antibody SYNI antibody
Fig1: Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti- phospho-Synapsin Ⅰ (S9) antibody. Counter stained with hematoxylin.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti- phospho-Synapsin Ⅰ (S9) antibody. Counter stained with hematoxylin.
Positive Control
Rat brain tissue, mouse brain tissue.
Application Notes
WB:1:1,000 IHC:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
