| 存储条件 |
|---|
| Product Name | GRIA2 [A3-A7] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AMPA 2 antibody AMPA selective glutamate receptor 2 antibody AMPA-selective glutamate receptor 2 antibody AMPA2 antibody GluA2 antibody GLUR 2 antibody GLUR B antibody GluR K2 antibody GluR-2 antibody GluR-B antibody GluR-K2 antibody GLUR2 antibody GLURB antibody Glutamate receptor 2 antibody Glutamate receptor ionotropic AMPA 2 antibody Glutamate receptor ionotropic antibody Gria2 antibody GRIA2_HUMAN antibody HBGR2 antibody |
| Product description | Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WBIHCFC |
| WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | AMPA 2 antibody AMPA selective glutamate receptor 2 antibody AMPA-selective glutamate receptor 2 antibody AMPA2 antibody GluA2 antibody GLUR 2 antibody GLUR B antibody GluR K2 antibody GluR-2 antibody GluR-B antibody GluR-K2 antibody GLUR2 antibody GLURB antibody Glutamate receptor 2 antibody Glutamate receptor ionotropic AMPA 2 antibody Glutamate receptor ionotropic antibody Gria2 antibody GRIA2_HUMAN antibody HBGR2 antibody |
|---|---|
| Molecular Weight(MW) | 99 kDa |
| Cellular Localization | Cell membrane. Endoplasmic reticulum membrane |
| SwissProt ID | P42262 |
|---|
Application
Fig1: Western blot analysis of Glutamate receptor 2 on human GRIA2 recombinant protein using anti- Glutamate receptor 2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of Glutamate receptor 2 on HEK293 (1) and Glutamate receptor 2-hIgGFc transfected HEK293 (2) cell lysate using anti- Glutamate receptor 2 antibody at 1/1,000 dilution.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using anti- Glutamate receptor 2 antibody. Counter stained with hematoxylin.
Application
Fig4: Flow cytometric analysis of SK-N-SH cells with Glutamate receptor 2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human Glutamate receptor 2 recombinant protein, Glutamate receptor 2-hIgGFc transfected HEK293 cell lysate, human rectum cancer tissues, SK-N-SH. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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