Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Fig1: Western blot analysis of TFF2 on human TFF2 recombinant protein using anti-TFF2 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of TFF2 on HEK293 (1) and TFF2-hIgGFc transfected HEK293 (2) cell lysate using anti-TFF2 antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with TFF2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Positive Control
Hela, human TFF2 recombinant protein.TFF2-hIgGFc transfected HEK293 cell lysate.
Application Notes
WB:1:500-1:2,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.