| 存储条件 |
|---|
| Product Name | ADD1 [H1-D4] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADD A antibody ADD1 antibody ADDA antibody ADDA_HUMAN antibody Adducin 1 (alpha) antibody Alpha adducin antibody Alpha-adducin antibody Erythrocyte adducin alpha subunit antibody Erythrocyte adducin subunit alpha antibody MGC3339 antibody MGC44427 antibody OTTHUMP00000151163 antibody OTTHUMP00000151164 antibody OTTHUMP00000151165 antibody OTTHUMP00000218664 antibody OTTHUMP00000218665 antibody |
| Product description | Adducins are a family of cytoskeleton proteins encoded by three genes (α, β, γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | ADD A antibody ADD1 antibody ADDA antibody ADDA_HUMAN antibody Adducin 1 (alpha) antibody Alpha adducin antibody Alpha-adducin antibody Erythrocyte adducin alpha subunit antibody Erythrocyte adducin subunit alpha antibody MGC3339 antibody MGC44427 antibody OTTHUMP00000151163 antibody OTTHUMP00000151164 antibody OTTHUMP00000151165 antibody OTTHUMP00000218664 antibody OTTHUMP00000218665 antibody |
|---|---|
| Molecular Weight(MW) | 81 kDa |
| Cellular Localization | Cytoplasm, cytoskeleton, cell membrane |
| SwissProt ID | P35611 |
|---|
Application
Fig1: Western blot analysis of alpha Adducin on human alpha Adducin recombinant protein using anti- alpha Adducin antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of alpha Adducin on HEK293 (1) and alpha Adducin -hIgGFc transfected HEK293 (2) cell lysate using anti- alpha Adducin antibody at 1/1,000 dilution.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti- alpha Adducin antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti- alpha Adducin antibody. Counter stained with hematoxylin.| Positive Control | Human alpha Adducin recombinant protein, alpha Adducin -hIgGFc transfected HEK293 cell lysate, human cervical cancer tissue, human rectum cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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