| 存储条件 |
|---|
| Product Name | TCL1A [5E-3A] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Anti TCL1A antibody Lymphoma/leukemia, T-cell antibody Oncogene TCL-1 antibody Oncogene TCL1 antibody P14 TCL1 antibody P14 TCL1 protein antibody Protein p14 TCL1 antibody T cell leukemia 1 antibody T cell lymphoma 1 antibody T cell lymphoma 1A antibody T-cell leukemia/lymphoma 1A antibody T-cell leukemia/lymphoma protein 1A antibody TCL 1 protein antibody TCL1 antibody TCL1 oncogene antibody TCL1 PEN antibody Tcl1a antibody TCL1A antibody antibody TCL1A_HUMAN antibody |
| Product description | T-cell Leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (T-PLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.1. TCL-1A is a member of a unique family of beta barrel proteins that bind small hydrophobic ligands and function in cell regulation. TCL-1A is an all-beta protein containing an eight-stranded antiparallel beta barrel which consists of two four-stranded beta-meander motifs. The two motifs are related by a twofold axis and connected by a long loop. TCL-1A forms a tight crystallographic dimer. TCL-1A is expressed in pre-B cells, in immature thymocytes, at low levels in activated T cells, and in the cytoplasm. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Anti TCL1A antibody Lymphoma/leukemia T-cell antibody Oncogene TCL-1 antibody Oncogene TCL1 antibody P14 TCL1 antibody P14 TCL1 protein antibody Protein p14 TCL1 antibody T cell leukemia 1 antibody T cell lymphoma 1 antibody T cell lymphoma 1A antibody T-cell leukemia/lymphoma 1A antibody T-cell leukemia/lymphoma protein 1A antibody TCL 1 protein antibody TCL1 antibody TCL1 oncogene antibody TCL1 PEN antibody Tcl1a antibody TCL1A antibody antibody TCL1A_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 14 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Microsome |
| SwissProt ID | P56279 |
|---|
Application
Fig1: Western blot analysis of TCL1A on human TCL1A recombinant protein using anti-TCL1A antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of TCL1A on HEK293 (1) and TCL1A-hIgGFc transfected HEK293 (2) cell lysate using anti-TCL1A antibody at 1/1,000 dilution.
Application
Fig3: Flow cytometric analysis of Hela cells with TCL1A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human TCL1A recombinant protein, TCL1A-hIgGFc transfected HEK293 cell lysate, Hela. |
|---|---|
| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
抱歉，暂无相关文献
