| 存储条件 |
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| Product Name | SSTR3 [5H-8E] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OTTHUMP00000028737 antibody Smstr 3 antibody Smstr3 antibody Somatostatin receptor subtype 3 antibody Somatostatin receptor type 3 antibody SS 3R antibody SS-3-R antibody SS3-R antibody SS3R antibody SSR 28 antibody SSR-28 antibody SSR28 antibody SSR3_HUMAN antibody Sst 3 antibody Sst3 antibody SSTR 3 antibody SSTR3 antibody |
| Product description | There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary. Somatostatin receptor type 3 (SSTR3) is a Somatostatin Receptor. Unlike SSTR1 and SSTR2, SSTR3 is functionally coupled to adenylyl cyclase. Expression of SSTR3 has been reported in brain, breast, eye, gastrointestinal tract, pancreas, and thyroid. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBFC |
| WB:1:500-1:2,000 FC:1:50-1:100 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | OTTHUMP00000028737 antibody Smstr 3 antibody Smstr3 antibody Somatostatin receptor subtype 3 antibody Somatostatin receptor type 3 antibody SS 3R antibody SS-3-R antibody SS3-R antibody SS3R antibody SSR 28 antibody SSR-28 antibody SSR28 antibody SSR3_HUMAN antibody Sst 3 antibody Sst3 antibody SSTR 3 antibody SSTR3 antibody |
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| Molecular Weight(MW) | 46 kDa |
| Cellular Localization | Cell membrane. |
| SwissProt ID | P32745 |
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Application
Fig1: Western blot analysis of SSTR3 on human SSTR3 recombinant protein using anti-SSTR3 antibody at 1/1,000 dilution.
Application
Fig2: Western blot analysis of SSTR3 on HEK293 (1) and SSTR3-hIgGFc transfected HEK293 (2) cell lysate using anti-SSTR3 antibody at 1/1,000
Application
Fig3: Western blot analysis of SSTR3 on different cell lysate using anti-SSTR3 antibody at 1/1,000 dilution. Positive control： Line1: Hela Line2: PANC-1 Line3: PC-12 Line4: SK-N-SH Line5: U937 Line6: HepG2
Application
Fig4: Flow cytometric analysis of Hela cells with SSTR3 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).| Positive Control | Human SSTR3 recombinant protein, SSTR3-hIgGFc transfected HEK293 cell lysate, Hela, PANC-1, PC-12, SK-N-SH, U937, HepG2. |
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| Application Notes | WB:1:500-1:2,000 FC:1:50-1:100 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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