Err 1 antibody ERR a antibody ERR alpha antibody ERR-alpha antibody Err1 antibody ERR1 protein antibody ERR1_HUMAN antibody ERRa antibody ERRalpha antibody ESRL 1 antibody ESRL1 antibody ESRR A antibody Esrra antibody Estrogen receptor like 1 antibody Estrogen receptor related 1 antibody estrogen receptor related receptor alpha antibody Estrogen receptor-like 1 antibody Estrogen related receptor alpha antibody Estrogen-related receptor alpha antibody Estrra antibody hERR1 antibody NR3B1 antibody Nuclear receptor subfamily 3 group B member 1 antibody Steroid hormone receptor ERR1 antibody
Product description
Estrogen related receptor alpha (ERRα) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of α, β and γ). ERRα plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRα has been shown to increase during fasting and cold exposure. ERRα may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRα are unable to maintain their body temperature in the cold. ERRα may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBIPFC
WB:1:1,000-1:2,000 FC:1:50-1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
Err 1 antibody ERR a antibody ERR alpha antibody ERR-alpha antibody Err1 antibody ERR1 protein antibody ERR1_HUMAN antibody ERRa antibody ERRalpha antibody ESRL 1 antibody ESRL1 antibody ESRR A antibody Esrra antibody Estrogen receptor like 1 antibody Estrogen receptor related 1 antibody estrogen receptor related receptor alpha antibody Estrogen receptor-like 1 antibody Estrogen related receptor alpha antibody Estrogen-related receptor alpha antibody Estrra antibody hERR1 antibody NR3B1 antibody Nuclear receptor subfamily 3 group B member 1 antibody Steroid hormone receptor ERR1 antibody
Fig1: Western blot analysis of Estrogen Related Receptor alpha on MCF-7 cell lysates using anti-Estrogen Related Receptor alpha antibody at 1/1,000 dilution.
Application
Fig2: Flow cytometric analysis of Hela cells with Estrogen Related Receptor alpha antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
Positive Control
MCF-7.
Application Notes
WB:1:1,000-1:2,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
