| 存储条件 |
|---|
| Product Name | Cytokeratin 10 [ST05-43] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCIE antibody BIE antibody CK 10 antibody CK-10 antibody Cytokeratin-10 antibody EHK antibody K10 antibody K1C10_HUMAN antibody Keratin 10 antibody Keratin antibody Keratin type i cytoskeletal 10 antibody Keratin type I cytoskeletal 59 kDa antibody Keratin-10 antibody Keratin10 antibody KPP antibody KRT10 antibody type I cytoskeletal 10 antibody |
| Product description | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHC |
| WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BCIE antibody BIE antibody CK 10 antibody CK-10 antibody Cytokeratin-10 antibody EHK antibody K10 antibody K1C10_HUMAN antibody Keratin 10 antibody Keratin antibody Keratin type i cytoskeletal 10 antibody Keratin type I cytoskeletal 59 kDa antibody Keratin-10 antibody Keratin10 antibody KPP antibody KRT10 antibody type I cytoskeletal 10 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| Cellular Localization | Cytoplasm. |
Application
Fig1: Western blot analysis of Cytokeratin 10 on Hela cell lysates using anti-Cytokeratin 10 antibody at 1/1,000 dilution.
Application
Fig2: ICC staining Cytokeratin 10 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 10 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 10 antibody. Counter stained with hematoxylin.| Positive Control | Hela, human tonsil tissue, mouse skin tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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