Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody
Product description
Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Immunogen
Synthetic peptide within human KHSRP aa 600-700.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Mouse
Tested Applications
WBFC
WB:1:500-1:2,000 FC:1:50-1:100
Species Reactivity
HumanMouseRat
Concentration
2mg/ml
Target Information
Alternative Names
Far upstream element-binding protein 2 antibody FBP2 antibody FUBP2 antibody FUBP2_HUMAN antibody FUSE binding protein 2 antibody FUSE-binding protein 2 antibody KH type splicing regulatory protein (FUSE binding protein 2) antibody KH type splicing regulatory protein antibody KH type-splicing regulatory protein antibody KHSRP antibody KSRP antibody p75 antibody
Fig1: Western blot analysis of KHSRP on Jurkat cell lysate using anti-KHSRP antibody at 1/500 dilution.
Application
Fig2: Flow cytometric analysis of HT-29 cells with KHSRP antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-mouse IgG was used as the secondary antibody.
Positive Control
Jurkat, HT-29.
Application Notes
WB:1:500-1:2,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
