| 存储条件 |
|---|
| Product Name | Rab5 [ST47-04] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAB 5 antibody RAB 5A antibody RAB5A antibody RAB5A member RAS oncogene family antibody RAB5A_HUMAN antibody RAS associated protein RAB5A antibody Ras related protein Rab 5A antibody Ras-related protein Rab-5A antibody |
| Product description | The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the Sec4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000 IHC:1:50-1:200: | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RAB 5 antibody RAB 5A antibody RAB5A antibody RAB5A member RAS oncogene family antibody RAB5A_HUMAN antibody RAS associated protein RAB5A antibody Ras related protein Rab 5A antibody Ras-related protein Rab-5A antibody |
|---|---|
| Molecular Weight(MW) | 24 kDa |
| Cellular Localization | Cell membrane, Cytoplasm, Cell projection, Membrane. |
Application
Fig1: Western blot analysis of Rab5 on different lysates using anti-Rab5 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: MCF-7
Application
Fig2: Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Rab5 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-Rab5 antibody. Counter stained with hematoxylin.| Positive Control | MCF-7, Hela, mouse brain tissue, mouse prostate tissue. |
|---|---|
| Application Notes | WB:1:1,000 IHC:1:50-1:200: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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