| 存储条件 |
|---|
| Product Name | YY1 [SY29-01] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CF1 antibody Delta antibody Delta transcription factor antibody INO80 complex subunit S antibody INO80S antibody NF E1 antibody NF-E1 antibody NFE1 antibody OTTHUMP00000197459 antibody Transcriptional repressor protein YY1 antibody TYY1_HUMAN antibody UCR motif DNA binding protein antibody UCRBP antibody Yin and yang 1 antibody Yin and Yang 1 protein antibody Yin Yang 1 antibody Ying Yang 1 antibody YY 1 antibody YY 1 transcription factor antibody YY-1 antibody YY1 antibody YY1 transcription factor antibody |
| Product description | The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain μE1 site as well as the P5 promoter of the adeno-associated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBICC/IFIHCIP |
| WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CF1 antibody Delta antibody Delta transcription factor antibody INO80 complex subunit S antibody INO80S antibody NF E1 antibody NF-E1 antibody NFE1 antibody OTTHUMP00000197459 antibody Transcriptional repressor protein YY1 antibody TYY1_HUMAN antibody UCR motif DNA binding protein antibody UCRBP antibody Yin and yang 1 antibody Yin and Yang 1 protein antibody Yin Yang 1 antibody Ying Yang 1 antibody YY 1 antibody YY 1 transcription factor antibody YY-1 antibody YY1 antibody YY1 transcription factor antibody |
|---|---|
| Molecular Weight(MW) | 68 kDa |
| Cellular Localization | Nucleus matrix. |
Application
Fig1: Western blot analysis of YY1 on different lysates using anti-YY1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: Jurkat Lane 3: HL-60
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-YY1 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-YY1 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-YY1 antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-YY1 antibody. Counter stained with hematoxylin.
Application
Fig6: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-YY1 antibody. Counter stained with hematoxylin.| Positive Control | Jurkat, HL-60, Hela, human tonsil tissue, human breast carcinoma tissue, human kidney tissue, mouse testis tissue, mouse colon tissue. |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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