| 存储条件 |
|---|
| Product Name | GPX4 [JU11-31] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Glutathione peroxidase 4 antibody GPX 4 antibody GPX-4 antibody GPX4 antibody GPX4_HUMAN antibody GSHPx-4 antibody MCSP antibody mitochondrial antibody PHGPx antibody Phospholipid hydroperoxidase antibody Phospholipid hydroperoxide glutathione peroxidase antibody Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody snGPx antibody snPHGPx antibody Sperm nucleus glutathione peroxidase antibody |
| Product description | Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Recombinant rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2,000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRatZebra Fish |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Alternative Names | Glutathione peroxidase 4 antibody GPX 4 antibody GPX-4 antibody GPX4 antibody GPX4_HUMAN antibody GSHPx-4 antibody MCSP antibody mitochondrial antibody PHGPx antibody Phospholipid hydroperoxidase antibody Phospholipid hydroperoxide glutathione peroxidase antibody Phospholipid hydroperoxide glutathione peroxidase mitochondrial antibody snGPx antibody snPHGPx antibody Sperm nucleus glutathione peroxidase antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa Clone number: JU11-31 |
| Cellular Localization | Mitochondrion. |
Application
Fig1: Western blot analysis of GPX4 on different lysates using anti-GPX4 antibody at 1/500 dilution. Positive control: Lane 1: Rat liver Lane 2: Mouse kidney Lane 3: Human liver Lane 4: Jurkat
Application
Fig2: Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-GPX4 antibody. Counter stained with hematoxylin.
Application
Fig5: Western blot analysis of GPX4 on Zebrafish tissue lysates using anti-GPX4 antibody at 1/500 dilution.| Positive Control | Rat liver tissue lysate, Jurkat, mouse kidney tissue lysate, human liver tissue lysate, Zebrafish tissue lysates, LOVO, MCF-7, PC-3M, rat epididymis tissue, human kidney tissue, mouse testis tissue. |
|---|---|
| Application Notes | WB:1:500-1:2,000 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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