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Ki-67 (8D5) Mouse mAb

产品编号 : 9449S

英文名称 :

中文名称 : 抗体

品牌 : CST

包装规格	交货周期	质量标准	目录价	会员专享价	数量
100 µl	现货2-3天	原装正品	￥4550	登录后可见	- +

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基础信息产品详情相关文献

基础信息

存储条件	-20℃

产品详情

Product Usage Information

Application	Dilution
Immunohistochemistry (Paraffin)	1:800 - 1:3200
Immunofluorescence (Immunocytochemistry)	1:1600 - 1:6400
Flow Cytometry (Fixed/Permeabilized)	1:100 - 1:400

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

For a carrier-free (BSA and azide free) version of this product see product #62548.

Specificity / Sensitivity

Ki-67 (8D5) Mouse Monoclonal Antibody recognizes endogenous levels of total Ki-67 protein.

Species Reactivity:

Human, Monkey

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human Ki-67 protein.

Background

Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein (1) that is universally expressed among proliferating cells and absent in quiescent cells (2). Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival (3). Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases (4).

Alternate Names

antigen identified by monoclonal antibody Ki-67; Antigen KI-67; Antigen Ki67; KI-67; KI67; KIA; marker of proliferation Ki-67; MIB-; MIB-1; MKI67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105

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