| 存储条件 |
|---|
| Product Name | Rabbit polyclonal antibody to Phospho-TRPV1(Ser502) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human TRPV1(Accession Q8NER1), corresponding to amino acid residues around phosphorylated Ser502. |
| Modification | p-Ser502 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:1000-1:3000 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TRPV1 |
|---|---|
| Gene Synonyms | VR1 |
| Gene Full Name | transient receptor potential cation channel subfamily V member 1 |
| Gene Summary | Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | Capsaicin receptor DKFZp434K0220 osm 9 like TRP channel 1 Osm-9-like TRP channel 1 OTRPC1 Transient receptor potential cation channel subfamily V member 1 TRPV 1 Trpv1 TRPV1_HUMAN Vanilloid receptor 1 Vanilloid receptor subtype 1 VR 1 VR1 |
| Molecular Weight(MW) | 95kDa |
| Cellular Localization | Cell junction>Synapse>Postsynaptic cell membrane>Multi-pass membrane protein. |
WB
TRPV1 in GABAergic neurons of the vlPAG in CPA mice.
IHC
Phospho-TRPV1(Ser502) Antibody at 1/100 staining Human mammary cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.| Application Notes | WB:1:1000-1:3000 IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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