| 存储条件 |
|---|
| Product Name | Keap1 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF-PIHCWB |
| WB:1:2000-1:10000 IHC:1:200-1:1000 IF-P:1:200-1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | KEAP1 |
|---|---|
| Gene Synonyms | INrf2 KLHL19 |
| Gene Full Name | kelch like ECH associated protein 1 |
| Gene Summary | This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | KEAP1 INRF2 KIAA0132 KLHL19 Kelch-like ECH-associated protein 1 Cytosolic inhibitor of Nrf2 INrf2 Kelch-like protein 19 |
| Molecular Weight(MW) | 70kDa(Calculated),60-70kDa(Observed). |
| Cellular Localization | Cytoplasm, Nucleus. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Keap1 antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: HEK293 Lane 2: RAW264.7 Lane 3: Rat spleen.
IHC
Mouse brain was stained with anti-Keap1 rabbit antibody.
IHC
Mouse kidney was stained with anti-Keap1 Rabbit antibody.
IF-P
Mouse kidney was stained with anti-Keap1 Rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:200-1:1000 IF-P:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
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