| 存储条件 |
|---|
| Product Name | ABCA1 Mouse Monoclonal AntibodyAntibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | 50kDa N-terminal extracellular loop of ABCA1 |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FCIHCWB |
| WB:1:2000 IHC:1:400 FC:1ug per million cells | |
| Species Reactivity | HumanMonkeyRat |
| Purification | Protein G |
| Gene Symbol | ABCA1 |
|---|---|
| Gene Synonyms | TGD ABC1 CERP ABC-1 HDLDT1 HPALP1 HDLCQTL13 |
| Gene Full Name | ATP binding cassette subfamily A member 1 |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019] |
| Molecular Weight(MW) | 254kDa |
| Cellular Localization | Cell membrane,Endosome. |
WB
Western Blot: ABCA1 Antibody Detection of ABCA1 in wildtype liver tissue (in RIPA) Lane 1: KO mouse liver tissue. Lane 2: WT mouse liver tissue.
IHC
ABCA1 Antibody - Analysis of ABCA1 in human renal cancer using DAB with hematoxylin counterstain.
FC
ABCA1 Antibody - Staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using ABCA1 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used.| Application Notes | WB:1:2000 IHC:1:400 FC:1ug per million cells |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C as received. Stable for 12 months from date of receipt. |
| Storage Buffer | PBS containing protease inhibitors and Sodium Azide. |
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