The immunogen for Anti-ROR1 Antibody: Peptide with sequence C-GNKSQKPYKIDSKQA, from the C-Terminus (near) of the protein sequence according to NP_005003.2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Goat
Tested Applications
IHC
IHC:3-6ug/ml
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ROR1
Gene Synonyms
NTRKR1 dJ537F10.1
Gene Full Name
receptor tyrosine kinase like orphan receptor 1
Gene Summary
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
Cellular Localization
Membrane.
Application
IHC
ROR1 antibody (6µg/ml) staining of paraffin embedded Human Prostate. Heat induced antigen retrieval with citrate buffer pH6, HRP-staining.
Application Notes
IHC:3-6ug/ml
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C as received.
Storage Buffer
Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
