| 存储条件 |
|---|
| Product Name | DRP1 Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:1000-1:5000 IHC:1:200-1:1000 ICC/IF:1:200-1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | DNM1L |
|---|---|
| Gene Synonyms | DLP1 DRP1 DVLP EMPF OPA5 EMPF1 DYMPLE HDYNIV |
| Gene Full Name | dynamin 1 like |
| Gene Summary | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
| Alternative Names | DNM1L DLP1 DRP1 Dynamin-1-like protein Dnm1p/Vps1p-like protein DVLP Dynamin family member proline-rich carboxyl-terminal domain less Dymple Dynamin-like protein Dynamin-like protein 4 Dynamin-like protein IV HdynIV Dynamin-rela |
| Molecular Weight(MW) | 83kDa |
| Cellular Localization | Cytoplasm. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-DRP1 antibody. The HRP conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Rat brain, Lane 2: Mouse brain.
IHC
Rat brain was stained with Anti-DRP1 rabbit antibody.
ICC/IF
Immunofluorescence analysis of Hela cell. 1,primary Antibody(green) was diluted at 1:200(4° overnight). 2, Goat Anti Rabbit Alexa Fluor 488 was diluted at 1:1000(room temperature, 50min). 3 DAPI(blue) 10min.| Application Notes | WB:1:1000-1:5000 IHC:1:200-1:1000 ICC/IF:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
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