This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Alternative Names
KLK-L6
Molecular Weight(MW)
29kDa
Cellular Localization
Secreted.
Application
WB
Gel: 10%SDS-PAGE Lysate: 40ug Lane: PC3 cells Primary antibody: KLK14 Antibody at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes.
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using KLK14 Antibody at dilution 1/40.(Original magnification: ×200)
