| 存储条件 |
|---|
| Product Name | Mouse Monoclonal Antibody to ABCA1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Purified recombinant fragment of human ABCA1 (AA: 2081-2261) expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | FCICC/IFIHC |
| IHC:1:100-1:500 ICC:1:200-1:1000 FC:1:200-1:400 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ABCA1 |
|---|---|
| Gene Synonyms | TGD ABC1 CERP ABC-1 HDLDT1 HPALP1 HDLCQTL13 |
| Gene Full Name | ATP binding cassette subfamily A member 1 |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency. [provided by RefSeq, Sep 2019] |
| Alternative Names | TGD ABC1 CERP ABC-1 HDLDT1 HPALP1 HDLCQTL13 |
| Molecular Weight(MW) | 254kDa |
| Cellular Localization | Cell membrane,Endosome. |
IHC
Immunohistochemical analysis of paraffin embedded Mouse spleen using ABCA1 mouse mAb with DAB staining.
IHC
Immunohistochemical analysis of paraffin embedded Rat spleen using ABCA1 mouse mAb with DAB staining.
ICC/IF
Immunofluorescence analysis of Hela cells using ABCA1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
FC
Flow cytometric analysis of bel-7402 cells using ABCA1 mouse mAb (green) and negative control (red).| Application Notes | IHC:1:100-1:500 ICC:1:200-1:1000 FC:1:200-1:400 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
抱歉，暂无相关文献
