| 存储条件 |
|---|
| Product Name | CD177 Mouse Monoclonal Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | CD177 (AAH29167, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB:1:500 IHC:1:200 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CD177 |
|---|---|
| Gene Synonyms | NB1 PRV1 HNA2A PRV-1 HNA-2a NB1 GP |
| Gene Full Name | CD177 molecule |
| Gene Summary | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014] |
| Alternative Names | NB1 PRV1 HNA-2a HNA2a |
| Molecular Weight(MW) | 46kDa |
| Cellular Localization | Cell membrane,Cell projection,Membrane,Secreted. |
WB
Western Blot analysis of CD177 expression in transfected 293T cell line by CD177 monoclonal antibody.
IHC
Human Spleen: Formalin-Fixed, Paraffin embedded (FFPE)| Application Notes | WB:1:500 IHC:1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Storage Buffer | PBS, pH 7.2 State: Purified State: Liquid purified Ig fraction |
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