| 存储条件 |
|---|
| Product Name | CD206 Monoclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | IF-PIHCIPWB |
| WB:1:5000-1:50000 IHC:1:10000-1:40000 IF-P:1:200-1:800 IP:0.5-4.0ug for 1.0-3.0mg of total protein lysate | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MRC1 |
|---|---|
| Gene Synonyms | MMR hMR CD206 MRC1L1 CLEC13D CLEC13DL bA541I19.1 |
| Gene Full Name | mannose receptor C-type 1 |
| Gene Summary | The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015] |
| Alternative Names | 2A6A10 CLEC13D CLEC13DL C-type lectin domain family 13 member D C-type lectin domain family 13 member D-like |
| Molecular Weight(MW) | 170kDa |
| Cellular Localization | Endosome membrane,Cell membrane. |
WB
human placenta tissue was subjected to SDS PAGE followed by western blot with CD206 antibody at dilution of 1:10000 incubated at room temperature for 1.5 hours.
IHC
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using CD206 antibody at dilution of 1:20000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
IF-P
Immunofluorescent analysis of (4% PFA) fixed human lung cancer tissue using CD206 antibody at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L).
IP
IP result of anti-CD206 (IP:5ug; Detection:1:300) with human placenta tissue lysate 1000ug.| Application Notes | WB:1:5000-1:50000 IHC:1:10000-1:40000 IF-P:1:200-1:800 IP:0.5-4.0ug for 1.0-3.0mg of total protein lysate |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. Stable for one year after shipment. |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
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