| 存储条件 |
|---|
| Product Name | Rabbit polyclonal antibody to IL15 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human IL15(Accession P40933), corresponding to amino acid residues S102-V152. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:500-1:2000 IHC:1:50-1:200 ICC:1:50-1:200 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IL15 |
|---|---|
| Gene Full Name | interleukin 15 |
| Gene Summary | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011] |
| Alternative Names | IL 15 IL-15 IL15 IL15_HUMAN Interleukin 15 Interleukin-15 Interleukin15 MGC9721 |
| Molecular Weight(MW) | 18kDa |
| Cellular Localization | Secreted,Cytoplasm,Nucleus. |
WB
Western blot analysis of IL15 expression in fetal liver lysates.
IHC
IHC analysis of IL-15 in the ovaries of two groups of mice. The brown part represents the part of IL-15 expression.
ICC/IF
Red fluorescence shows ovarian granulosa cells IL-15.| Application Notes | WB:1:500-1:2000 IHC:1:50-1:200 ICC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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