| 存储条件 |
|---|
| Product Name | MMP-9 [2G3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 82 kDa matrix metalloproteinase-9 antibody 92 kDa gelatinase antibody 92 kDa type IV collagenase antibody CLG 4B antibody CLG4B antibody Collagenase Type 4 beta antibody Collagenase type IV 92 KD antibody EC 3.4.24.35 antibody Gelatinase 92 KD antibody Gelatinase B antibody Gelatinase beta antibody GelatinaseB antibody GELB antibody Macrophage gelatinase antibody MANDP2 antibody Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody Matrix Metalloproteinase 9 antibody MMP 9 antibody MMP-9 antibody MMP9 antibody MMP9_HUMAN antibody Type V collagenase antibody |
| Product description | The matrix metallo proteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc (3). MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression. |
| Immunogen | Amino acids 603-614 of MMP-9 of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIPIFIHC-P |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | 82 kDa matrix metalloproteinase-9 antibody 92 kDa gelatinase antibody 92 kDa type IV collagenase antibody CLG 4B antibody CLG4B antibody Collagenase Type 4 beta antibody Collagenase type IV 92 KD antibody EC 3.4.24.35 antibody Gelatinase 92 KD antibody Gelatinase B antibody Gelatinase beta antibody GelatinaseB antibody GELB antibody Macrophage gelatinase antibody MANDP2 antibody Matrix metallopeptidase 9 (gelatinase B 92kDa gelatinase 92kDa type IV collagenase) antibody Matrix Metalloproteinase 9 antibody MMP 9 antibody MMP-9 antibody MMP9 antibody MMP9_HUMAN antibody Type V collagenase antibody |
|---|---|
| Molecular Weight(MW) | 92 kDa |
| Cellular Localization | Secreted |
| SwissProt ID | P14780 |
|---|
Application
Fig1: Western blot analysis of MMP-9 expression in human PBL whole cell lysate.
Application
Fig2： Immunoperoxidase staining of formalin-fixed, paraffin-embedded human heart tissue showing cytoplasmic staining.| Positive Control | PBL, human heart tissue. |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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