Ig gamma 4 chain C region antibody IGHG4 antibody immunoglobulin heavy chain constant region gamma 4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody
Product description
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
Immunogen
IgG4 of human origin.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
ICC/IF
ELISA:1:30-1:3,000
Species Reactivity
Human
Concentration
2mg/ml
Target Information
Alternative Names
Ig gamma 4 chain C region antibody IGHG4 antibody immunoglobulin heavy chain constant region gamma 4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody
