| 存储条件 |
|---|
| Product Name | COX IV |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AL024441 antibody COX 4 antibody COX IV 1 antibody COX IV antibody COX IV-1 antibody Cox4 antibody COX41_HUMAN antibody Cox4a antibody COX4B antibody COX4I1 antibody COX4I2 antibody COX4L2 antibody COXIV antibody Cytochrome c oxidase polypeptide IV antibody Cytochrome c oxidase subunit 4 isoform 1 mitochondrial antibody Cytochrome c oxidase subunit 4 isoform 1, mitochondrial antibody Cytochrome C Oxidase subunit IV antibody Cytochrome c oxidase subunit IV isoform 1 antibody Cytochrome c oxidase subunit IV isoform 2 (lung) antibody Cytochrome c oxydase subunit 4 antibody dJ857M17.2 antibody MGC105470 antibody MGC72016 antibody |
| Product description | Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta. |
| Immunogen | Amino acids 86-169 mapping at the C-terminus of COX4 of human origin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC-P |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | AL024441 antibody COX 4 antibody COX IV 1 antibody COX IV antibody COX IV-1 antibody Cox4 antibody COX41_HUMAN antibody Cox4a antibody COX4B antibody COX4I1 antibody COX4I2 antibody COX4L2 antibody COXIV antibody Cytochrome c oxidase polypeptide IV antibody Cytochrome c oxidase subunit 4 isoform 1 mitochondrial antibody Cytochrome c oxidase subunit 4 isoform 1 mitochondrial antibody Cytochrome C Oxidase subunit IV antibody Cytochrome c oxidase subunit IV isoform 1 antibody Cytochrome c oxidase subunit IV isoform 2 (lung) antibody Cytochrome c oxydase subunit 4 antibody dJ857M17.2 antibody MGC105470 antibody MGC72016 antibody |
|---|---|
| Molecular Weight(MW) | 17kDa |
| Cellular Localization | Mitochondrion inner membrane |
| SwissProt ID | P13073 |
|---|
Application
Fig1: Western blot analysis of COX4 expression in HepG2 (A), HeLa( B), MCF7 (C) and A-375 (D) whole cell lysates and human skeletal muscle tissue extract (E).
Application
Fig2： Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.| Positive Control | Hela, HepG2, MCF7, A-375, human skeletal muscle tissue, human heart muscle tissue. |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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