| 存储条件 |
|---|
| Product Name | CCR2/CKR2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C C chemokine receptor type 2 antibody C C CKR 2 antibody C-C chemokine receptor type 2 antibody C-C CKR-2 antibody CC chemokine receptor type 2 antibody CC CKR 2 antibody CC-CKR-2 antibody CCCKR2 antibody CCR 2 antibody CCR-2 antibody CCR1L antibody CCR2 antibody CCR2_HUMAN antibody CCR2A antibody CCR2B antibody CCR5L antibody CD192 antibody CD192 antigen antibody Chemokine C C motif receptor 2 antibody Chemokine CC Motif Receptor 2 antibody CKR 2 antibody CKR2 antibody CKR2A antibody CKR2B antibody CMKBR2 antibody MCP 1 R antibody MCP-1-R antibody MCP1 RECEPTOR antibody MCP1R antibody Monocyte chemoattractant protein 1 receptor antibody Monocyte Chemotactic Protein 1 Receptor antibody Monocyte Chemotactic Protein 1 Receptor antibody |
| Product description | C-C or b chemokine family members are characterized by a pair of adjacent cysteine residues and serve as potent chemoattractants and activators of monocytes and T cells. C-C chemokine receptor family members include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10 and the Duffy blood group antigen. Each of these receptors are G protein coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation. However, this receptor family has also been shown to facilitate viral infection. CKR-2 (C-C chemokine receptor type 2) is a 374 amino acid multi-pass membrane protein that belongs to the C-C chemokine receptor family and is expressed as two isoforms, designated CKR-2A and CKR-2B. Both CKR-2 isoforms function as receptors for a variety of proteins, including MCP-1 and MCP-3, thereby influencing intracellular calcium levels and affecting signal transduction throughout the cell. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIF |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | C C chemokine receptor type 2 antibody C C CKR 2 antibody C-C chemokine receptor type 2 antibody C-C CKR-2 antibody CC chemokine receptor type 2 antibody CC CKR 2 antibody CC-CKR-2 antibody CCCKR2 antibody CCR 2 antibody CCR-2 antibody CCR1L antibody CCR2 antibody CCR2_HUMAN antibody CCR2A antibody CCR2B antibody CCR5L antibody CD192 antibody CD192 antigen antibody Chemokine C C motif receptor 2 antibody Chemokine CC Motif Receptor 2 antibody CKR 2 antibody CKR2 antibody CKR2A antibody CKR2B antibody CMKBR2 antibody MCP 1 R antibody MCP-1-R antibody MCP1 RECEPTOR antibody MCP1R antibody Monocyte chemoattractant protein 1 receptor antibody Monocyte Chemotactic Protein 1 Receptor antibody Monocyte Chemotactic Protein 1 Receptor antibody |
|---|---|
| Molecular Weight(MW) | 47kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P51683 |
|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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