| 存储条件 |
|---|
| Product Name | Cytokeratin 13 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 47 kDa cytokeratin antibody CK-13 antibody CK13 antibody Cytokeratin 13 antibody Cytokeratin-13 antibody K13 antibody K1C13_HUMAN antibody Ka13 antibody Keratin 13 antibody Keratin antibody keratin type I cytoskeletal 13 antibody Keratin-13 antibody Krt-1.13 antibody Krt1-13 antibody KRT13 antibody MGC161462 antibody MGC3781 antibody type I cytoskeletal 13 antibody Type I keratin Ka13 antibody WSN2 antibody |
| Product description | Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 13 belongs to the intermediate filament family and is a heterotetramer of two type I acidic and two type II basic keratins. It is generally associated with cytokeratin 4. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. |
| Immunogen | Recombinant protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCICC |
| WB:1:500~1:2000 IHC:1:50~1:200 ICC:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | 47 kDa cytokeratin antibody CK-13 antibody CK13 antibody Cytokeratin 13 antibody Cytokeratin-13 antibody K13 antibody K1C13_HUMAN antibody Ka13 antibody Keratin 13 antibody Keratin antibody keratin type I cytoskeletal 13 antibody Keratin-13 antibody Krt-1.13 antibody Krt1-13 antibody KRT13 antibody MGC161462 antibody MGC3781 antibody type I cytoskeletal 13 antibody Type I keratin Ka13 antibody WSN2 antibody |
|---|---|
| Molecular Weight(MW) | 45/49 kDa |
| Cellular Localization | Cytoskeleton, Nucleus. |
Application
Fig1: Western blot analysis of Cytokeratin 13 on human skin tissue lysate using anti-Cytokeratin 13 antibody at 1/1,000 dilution.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 13 antibody. Counter stained with hematoxylin.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-Cytokeratin 13 antibody. Counter stained with hematoxylin.| Positive Control | Human skin tissue lysate, human tonsil tissue, mouse uterus tissue. |
|---|---|
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 ICC:1:200~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide. |
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