Amine oxidase [flavin containing] A antibody Amine oxidase [flavin-containing] A antibody AOFA antibody AOFA_HUMAN antibody EC 1.4.3.4 antibody MAO A antibody MAO-A antibody maoA antibody Monoamine oxidase A antibody Monoamine oxidase type A antibody
Product description
Monoamine oxidase A is an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the outer mitochondrial membrane. Its encoding gene is adjacent to a related gene (MAOB) on the opposite strand of the X chromosome. MAO-A levels in the brain as measured using positron emission tomography are elevated by an average of 34% in patients with major depressive disorder. Genetic association studies examining the relationship between high-activity MAOA variants and depression have produced mixed results, with some studies linking the high-activity variants to major depression in females, depressed suicide in males, major depression and sleep disturbance in males and major depressive disorder in both males and females.
Immunogen
recombinant protein
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:1000-1:2,000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
Amine oxidase [flavin containing] A antibody Amine oxidase [flavin-containing] A antibody AOFA antibody AOFA_HUMAN antibody EC 1.4.3.4 antibody MAO A antibody MAO-A antibody maoA antibody Monoamine oxidase A antibody Monoamine oxidase type A antibody