| 存储条件 |
|---|
| Product Name | JNK1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AI849689 antibody c Jun N terminal kinase 1 antibody C-JUN kinase 1 antibody c-Jun N-terminal kinase 1 antibody EC 2.7.11.24 antibody JNK 1 antibody JNK antibody JNK-46 antibody JNK1A2 antibody JNK21B1/2 antibody MAP kinase 8 antibody MAPK 8 antibody mapk8 antibody Mitogen activated protein kinase 8 antibody Mitogen-activated protein kinase 8 antibody MK08_HUMAN antibody p54 gamma antibody Prkm8 antibody Protein kinase JNK1 antibody Protein kinase, mitogen-activated, 8 antibody SAPK 1 antibody SAPK gamma antibody SAPK1 antibody Stress-activated protein kinase 1 antibody Stress-activated protein kinase JNK1 antibody |
| Product description | Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHCFC |
| WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 | |
| Species Reactivity | HumanMouseRatZebra Fish |
| Concentration | 1mg/ml |
| Alternative Names | AI849689 antibody c Jun N terminal kinase 1 antibody C-JUN kinase 1 antibody c-Jun N-terminal kinase 1 antibody EC 2.7.11.24 antibody JNK 1 antibody JNK antibody JNK-46 antibody JNK1A2 antibody JNK21B1/2 antibody MAP kinase 8 antibody MAPK 8 antibody mapk8 antibody Mitogen activated protein kinase 8 antibody Mitogen-activated protein kinase 8 antibody MK08_HUMAN antibody p54 gamma antibody Prkm8 antibody Protein kinase JNK1 antibody Protein kinase mitogen-activated 8 antibody SAPK 1 antibody SAPK gamma antibody SAPK1 antibody Stress-activated protein kinase 1 antibody Stress-activated protein kinase JNK1 antibody |
|---|---|
| Molecular Weight(MW) | ~48/54kDa |
| Cellular Localization | Cytoplasm, nucleus |
| SwissProt ID | P45983 |
|---|
Application
Fig1: Western blot analysis of JNK1 on different cell lysates using anti-JNK1 antibody at 1/1,000 dilution.Positive control:Lane 1: K562Lane 2: PC-12Lane 3: Hela
Application
Fig2: Western blot analysis of JNK1 on hybrid fish (crucian-carp) brain tissue lysate using anti-JNK1 antibody at 1/500 dilution.| Positive Control | Hela, K562, PC12 |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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