| 存储条件 |
|---|
| Product Name | BCL2L1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis. Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2. It appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBICCIHC |
| WB:1:500~1:2000 ICC:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | ~26kDa |
|---|---|
| Cellular Localization | Mitochondrion membrane, nucleus membrane, cytoplasm |
| SwissProt ID | Q07817 |
|---|
Application
Fig1: Western blot analysis on A431 and K562 cell lysates using anti-BCL2L1rabbit polyclonal antibodies.
Application
Fig2: Immunofluorescent staining of Hela cells using anti- BCL2L1 rabbit polyclonal antibody.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti- BCL2L1 rabbit polyclonal antibody.| Positive Control | Hela, A431, K562, human breast carcinoma tissue |
|---|---|
| Application Notes | WB:1:500~1:2000 ICC:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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