| 存储条件 |
|---|
| Product Name | UTF1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody |
| Product description | Undifferentiated embryonic cell transcription factor 1 (UTF1) is expressed in cells of the inner cell mass and the epiblast. Upon activation by Oct-3/4, UTF1 may be responsible for the rapid proliferation and tumorigenic properties of embryonic stem cells. Sox2 is also part of the Oct-3/4-containing complex able to bind the regulatory region of UTF1. UTF1 acts as a transcriptional coactivator of ATF2 and it binds to the N-terminal region of ATF2. Reduced expression in embryonic stem cells (ESCs) is associated with failure to differentiate properly, although self-renewal is unaffected. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1,000-1:2,000 IHC:1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 40 kDa |
| Cellular Localization | Cell nucleus |
| SwissProt ID | Q5T230 |
|---|
Application
Fig1: Western blot analysis on D3 cell lysates (1) and human brain tissue (2) using anti-UTF1 rabbit polyclonal antibodies.
Application
Fig2：Immunohistochemical analysis of paraffin-embedded human testis tissue using anti- UTF1 rabbit polyclonal antibodies.| Positive Control | Human brain, D3, human testis |
|---|---|
| Application Notes | WB:1:1,000-1:2,000 IHC:1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
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