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Recombinant Human PDGF-AB

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产品信息

应用
建议稀释比
已发表文章

对照试剂 (Ctrl)

Assay-dependent
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体外检测 (In vitro)

-

其他PubMed (Misc)

-

Bioactivity (Bioactivity)

Assay-dependent
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Cell differentiation (Cell Diff)

-
产品规格

种属

Human

已发表种属

Guinea pig, Human, Mouse, Non-human primate, Rat

Expression System

E. coli

氨基酸序列

Alpha chain: SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT Beta chain: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RPTQVQLRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TVAAARPVT

分子量

26.4 kDa

分类

Recombinant

类型

Protein

纯度

≥ 98% by SDS-PAGE gel and HPLC analyses.

内毒素浓度

<1 EU/µg

活性

The ED50 as determined by the dose-dependent stimulation of thymidine uptake by Balb/c 3T3 cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.

偶联物

Unconjugated

形式

Lyophilized

Amount

10 µg

纯化类型

purified

内含物

no preservative

保存条件

-20°C

运输条件

Ambient

产品详细信息

Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one alpha chain and one beta chain (234 total amino acids).

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

靶标信息

Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Human PDGF-AB Protein in Bioactivity (Bioactivity)

Human PDGF-AB Protein (100-00AB-10UG) in Bioactivity

Bioassay analysis of Human PDGF-AB Recombinant Protein, PeproTech® (Product # 100-00AB-1MG).


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