Anti-Dystrophin antibody [MANDRA1]

• 产品名称

  Anti-Dystrophin抗体[MANDRA1]
  参阅全部 Dystrophin 一抗

• 描述

  小鼠单克隆抗体[MANDRA1] to Dystrophin

• 宿主

  Mouse

• 经测试应用

  适用于: IHC-Fr, WB, ELISA, ICC/IFmore details
  不适用于: IHC-P

• 种属反应性

  与反应: Human
  预测可用于: Mouse, Rat, Fish

• 免疫原

  Recombinant fragment within Human Dystrophin aa 3200-3700. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.

• 表位

  128 amino acids at the end of the C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684).

• 阳性对照

• lympho blastoid cells, cultures of brain astroglial and neuronal cells, liver and Hep G2 cells

• 常规说明

  The C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx).

  This product was changed from ascites to tissue culture supernatant on 17 May 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

   

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

• 存储溶液

  Preservative: 0.0975% Sodium azide
  Constituent: 0.411% PBS

• 纯度

  Proprietary Purification

• 纯化说明

  Purified from culture supernatant of hybridoma cells with proprietary method.

• Primary antibody说明

  The C-terminal domain of the human dystrophin molecule (a.a. residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx).

• 克隆

  单克隆

• 克隆编号

  MANDRA1

• 同种型

  IgG1

The Abpromise guarantee

Abpromise™承诺保证使用ab7164于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

应用说明

Is unsuitable for IHC-P.

• 数据库链接

  hide

• Unigene: 495912 Human

• Unigene: 275608 Mouse

• Unigene: 416750 Mouse

• Unigene: 10307 Rat

• Entrez Gene: 1756 Human

• Entrez Gene: 13405 Mouse

• Entrez Gene: 24907 Rat

• NCBI: NP_004002.2 Human

• Omim: 300377 Human

• SwissProt: P11532 Human

• SwissProt: P11531 Mouse

• SwissProt: P11530 Rat

别名

• BMD antibody

• CMD3B antibody

• DMD antibody

• DMD_HUMAN antibody

• Duchenne muscular dystrophy protein antibody

• Dystrophin antibody

• Muscular dystrophy Duchenne and Becker types antibody

• 

  Immunohistochemistry (Frozen sections) - Anti-Dystrophin antibody [MANDRA1] (ab7164)

  ab7164 staining Dystrophin in frozen human tongue tissue sections by Immunohistochemistry (IHC - Fr- Frozen sections). Samples were incubated 1:100 dilution. A Goat Anti-mouse, FITC- conjugate was used as the secondary antibody. 

  This image was generated using the ascites version of the product.