GFR alpha 3/GFRA3多肽
参阅全部 GFR alpha 3/GFRA3 蛋白酶
No
Synthetic
Our Abpromise guarantee covers the use of ab6100 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用
Blocking
Liquid
Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novelglycosylphosphadidylinositol linked protein GFRa and Ret receptor tyrosine kinase GFRb. Following the discovery of GFRa-1 and -2, a novel receptor in GFRa family was identified recently in human and mouse and designated GFRa-3. GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
This product was previously labelled as GFR alpha 3
浓度
50 µg 浓度为 0.2 mg/ml
Shipped at 4°C. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
GDNF family receptor alpha 3
GDNF family receptor alpha-3
GDNF receptor alpha-3
GDNFR-alpha-3
GDNFR3
GFR-alpha-3
GFRA3
GFRA3_HUMAN
Glial cell line derived neurotrophic factor receptor alpha 3
GPI linked receptor
OTTHUMP00000159486
OTTHUMP00000224020
