Anti-BCMA抗体- C-terminal
参阅全部 BCMA 一抗
兔多克隆抗体to BCMA - C-terminal
Rabbit
适用于: ICC/IF, IHC-P, WBmore details
与反应: Human
Synthetic peptide corresponding to Human BCMA (C terminal).
Human spleen tissue lysate, K562 or U937 whole cell lysates.
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL1/THANK/zTNF4 and April/TALL2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFFR, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
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Liquid
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at +4°C.
pH: 7.2
Preservative: 0.02% Sodium azide
Immunogen affinity purified
BCMA Antibody is affinity chromatography purified via peptide column.
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL1/THANK/zTNF4 and April/TALL2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFFR, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
多克隆
IgG
Abpromise™承诺保证使用ab5972于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ICC/IF | Use a concentration of 10 - 20 µg/ml. | |
| IHC-P | Use a concentration of 1 - 5 µg/ml. | |
| WB | Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 20 kDa. |
Entrez Gene: 608 Human
Omim: 109545 Human
SwissProt: Q02223 Human
Unigene: 2556 Human
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCMA antibody - C-terminal (ab5972)
ab5972 at 10µg/ml staining BCMA in human spleen cells by IHC
Immunocytochemistry/ Immunofluorescence - Anti-BCMA antibody - C-terminal (ab5972)
Immunofluorescence of BCMA in Human Spleen cells using ab5972 at 10 ug/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCMA antibody - C-terminal (ab5972)
Immunohistochemistry of BCMA in human spleen tissue with BCMA antibody at 5 µg/ml.
