Anti-alpha COP I/COPA antibody

• 产品名称

  Anti-alpha COP I/COPA抗体
  参阅全部 alpha COP I/COPA 一抗

• 描述

  兔多克隆抗体to alpha COP I/COPA

• 宿主

  Rabbit

• 特异性

  Detects coatomer-protein I alpha (COP I alpha).

• 经测试应用

  适用于: ICC/IFmore details

• 种属反应性

  与反应: Human
  预测可用于: Mouse, Cow, Dog, Rice

• 免疫原

  Synthetic peptide corresponding to Rat alpha COP I/COPA aa 1-19.
  Sequence:

  MLTKFETKSARVKGLSFHP

  
  (Peptide available as ab4931)

  Run BLAST with Run BLAST with 

• 常规说明

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

  If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

• 存储溶液

  Preservative: 0.05% Sodium azide
  Constituents: 0.1% BSA, 99% PBS

• 浓度

• 100 µg 浓度为 1 mg/ml

• 纯度

  Immunogen affinity purified

• Primary antibody说明

  Coatomer proteins are involved in regulating transport between the endoplasmic reticulum (ER) and the Golgi complex and in intra-Golgi transport. There exist two coatomer-protein mechanisms (COP I and COP II) and although they have mechanistic parallels, they are molecularly distinct. The COP I coat is comprised of seven subunits (alpha-, beta-, beta'-, gamma-, delta-, epsilon-, and zeta-COP) in a complex called coatomer. Assembly of the coatomer (COP I) onto non-clathrin coated vesicles is regulated by ADP-ribosylation factor (ARF). Vesicle formation, budding, fusion, and disassembly is dependent on GDP-GTP exchange, COP I, and ARF. COP I has been shown to facilitate retrograde intracellular transport from the ER to the Golgi complex. By contrast, COPII facilitates anterograde transport between these subcellular organelles. COP II has been shown to be independently and selectively recruited to the ER relative to COP I subunits.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab2913于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

数据库链接

• Entrez Gene: 100126041 Cow

• Entrez Gene: 1314 Human

• Entrez Gene: 12847 Mouse

• Omim: 601924 Human

• SwissProt: Q27954 Cow

• SwissProt: P53621 Human

• SwissProt: Q8CIE6 Mouse

• Unigene: 162121 Human

• Unigene: 685025 Human

• Unigene: 30041 Mouse

别名

• Alpha coat protein antibody

• Alpha COP antibody

• Alpha COPI antibody

• Alpha-coat protein antibody

• Alpha-COP antibody

• AlphaCOP antibody

• Coatomer protein complex subunit alpha antibody

• Coatomer subunit alpha antibody

• COP A antibody

• COP I alpha antibody

• copA antibody

• COPA_HUMAN antibody

• COPI alpha antibody

• FLJ26320 antibody

• HEP COP antibody

• HEP-COP antibody

• HEPCOP antibody

• Proxenin antibody

• Xenin antibody

• Xenopsin-related peptide antibody

• 

  Immunocytochemistry/ Immunofluorescence - Anti-alpha COP I/COPA antibody (ab2913)

  ICC/IF of COP1 in Hela Cells