Anti-PP2A B subunit抗体
兔多克隆抗体to PP2A B subunit
Rabbit
Based on sequence homology we believe this antibody will detect the following isoforms of the PP2A B subunit. The immunogen sequence is 100% identical to Q16537; epsilon isoform (PPP2R5E), Q13362; gamma isoform (PPP2R5C), Q14738; delta isoform (PPP2R5D) and Q15173 beta isoform (PPP2R5B), and 92% identical to Q15172; alpha isoform (PPP2R5A). If the isoform you are interested in is not listed, please contact our technical support team on technical@abcam.com who will be happy to check that for you.
适用于: WBmore details
与反应: Mouse, Rat, Human
Synthetic peptide corresponding to Human PP2A B subunit aa 352-365 conjugated to Keyhole Limpet Haemocyanin (KLH). The sequence is also 100% identical to Q13362 (PPP2R5C), Q14738 (PPP2R5D) and Q15173 (PPP2R5B), and 92% identical to Q15172 (PPP2R5A).
Sequence:
VSSPHFQVAERALY
Database link: Q16537
WB: Rat brain extract and Recombinant Human PPP2R5D protein (ab114547)
A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein phosphorylation is one of the most common forms of reversible protein posttranslational modification (PTM), with up to 30% of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the effectors of phosphorylation and catalyse the transfer of a γ-phosphate from ATP to specific amino acids on proteins. Several hundred PKs exist in mammals and are classified into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 79.3, 16.9 and 3.8% respectively of the phosphoproteome, at least in mammals. In contrast, protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes based on sequence, structure and catalytic function. The largest class of PPs is the phosphoprotein phosphatase (PPP) family comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg2+ or Mn2+-dependent (PPM) family, composed primarily of PP2C.
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Liquid
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Preservative: 0.08% Sodium azide
Constituent: PBS
浓度
100 µg 浓度为 1 mg/ml
Ammonium Sulphate Precipitation
Purified by Ammonium sulfate precipitation.
多克隆
IgG
Abpromise™承诺保证使用ab16448于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | Use at an assay dependent concentration. |
SwissProt: Q13362 Human
SwissProt: Q14738 Human
SwissProt: Q15172 Human
SwissProt: Q15173 Human
SwissProt: Q16537 Human
PP2A B subunit isoform B'-delta antibody
PP2A B subunit isoform B'-epsilon antibody
PP2A B subunit isoform B'-gamma antibody
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PP2A B subunit isoform B56-beta antibody
PP2A B subunit isoform B56-delta antibody
PP2A B subunit isoform B56-epsilon antibody
PP2A B subunit isoform B56-gamma antibody
PP2A B subunit isoform PR61-alpha antibody
PP2A B subunit isoform PR61-beta antibody
PP2A B subunit isoform PR61-delta antibody
PP2A B subunit isoform PR61-epsilon antibody
PP2A B subunit isoform PR61-gamma antibody
PP2A B subunit isoform R5-alpha antibody
PP2A B subunit isoform R5-beta antibody
PP2A B subunit isoform R5-delta antibody
PP2A B subunit isoform R5-epsilon antibody
PP2A B subunit isoform R5-gamma antibody
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PPP2R5B antibody
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PPP2R5D antibody
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Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform antibody
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform antibody
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform antibody
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform antibody
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform antibody
KIAA0044 antibody
PP2A B subunit isoform B'-alpha antibody
PP2A B subunit isoform B'-beta antibody
