Anti-Prostaglandin E Receptor EP2/PTGER2抗体[3E6]
参阅全部 Prostaglandin E Receptor EP2/PTGER2 一抗
小鼠单克隆抗体[3E6] to Prostaglandin E Receptor EP2/PTGER2
Mouse
适用于: WBmore details
与反应: Cow
Recombinant fragment corresponding to Human Prostaglandin E Receptor EP2/PTGER2.
Database link: P43116
WB; Porcine brain lysate
Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. It's wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.
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Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.08% Sodium azide
Constituent: PBS
Protein A/G purified
单克隆
3E6
IgG1
Abpromise™承诺保证使用ab16151于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 53 kDa. |
PGE2 receptor EP2 subtype antibody
Prostaglandin E receptor 2 EP2 subtype antibody
Prostaglandin E receptor 2 subtype EP2 53kDa antibody
Prostaglandin E receptor 2 subtype EP2 antibody
Prostaglandin E2 receptor antibody
Prostaglandin E2 receptor EP2 subtype antibody
Prostanoid EP2 receptor antibody
Ptger2 antibody
EP2 antibody
PE2R2_HUMAN antibody
PGE receptor EP2 subtype antibody
Western blot - Anti-Prostaglandin E Receptor EP2/PTGER2 antibody [3E6] (ab16151)
ab16151 at 1ug/ml detecting Prostaglandin E Receptor EP2/PTGER2 from bovine brain lysate by Western blot