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Anti-C3/C3b antibody [11H9]

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产品详情
  • 产品名称

    Anti-C3抗体[11H9]
    参阅全部 C3/C3b 一抗

  • 描述

    大鼠单克隆抗体[11H9] to C3/C3b

  • 宿主

    Rat

  • 特异性

    This antibody recognizes both intact C3 and its cleaved products C3b, iC3b, C3d and C3dg. The mature protein C3 has a molecular weight of approximately 190 kDa. The complement factor C3 consists of an alpha- and a beta-chain, linked by disulfide bond. C3 convertase activates C3 by cleaving the alpha chain, releasing C3a anaphylotoxin and generating C3b (alpha chain and beta chain). C3b has a molecular weight of approximately 185 kDa. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. iC3b has a molecular weight of approximately 182 kDa. Does not cross react with C4.

  • 经测试应用

    适用于: ICC/IFmore details

  • 种属反应性

    与反应: Mouse

  • 免疫原

    C57BL/6 thymocytes saturated with rat anti-Thy-1 monoclonal antibody of IgG2b subclass (RmT1).

  • 常规说明

    In response to recent customer complaints for IHC-P with paraffin embedded sections we no longer guarantee this application.


    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

  • 形式

    Liquid

  • 存放说明

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • 存储溶液

    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.1% BSA

  • 浓度

    • 50 µg 浓度为 0.1 mg/ml

  • 纯度

    Protein G purified

  • 纯化说明

    0.2 µm filtered

  • 克隆

    单克隆

  • 克隆编号

    11H9

  • 同种型

    IgG2a

The Abpromise guarantee

Abpromise™承诺保证使用ab11862于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。

应用Ab评论说明
ICC/IF

Use at an assay dependent concentration.

  • 数据库链接

  • 别名

    • ASP antibody

    • C3 and PZP like alpha 2 macroglobulin domain containing protein 1 antibody

    • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody

    • C3 antibody

    • c3 complement antibody

    • C3adesArg antibody

    • CO3_HUMAN antibody

    • Complement C3 alpha chain antibody

    • Complement C3 antibody

    • Complement C3b alpha' chain antibody

    • Complement C3c alpha' chain fragment 1 antibody

    • Complement C3c alpha' chain fragment 2 antibody

    • Complement C3c alpha'' chain fragment 2 antibody

    • Complement C3d fragment antibody

    • Complement C3dg fragment antibody

    • Complement C3f fragment antibody

    • Complement C3g fragment antibody

    • Complement component 3 antibody

    • Complement factor 3 antibody

    • CPAMD1 antibody

    • HEL S 62p antibody

    • omplement C3 beta chain antibody

    • Acylation stimulating protein cleavage product antibody

    • AHUS5 antibody

    • ARMD9 antibody

  • Immunocytochemistry/ Immunofluorescence - Anti-C3 antibody [11H9] (ab11862)

    Immunocytochemistry/ Immunofluorescence - Anti-C3 antibody [11H9] (ab11862)

    ab11862 staining C3 in murine kidney cells by Immunocytochemistry/ Immunofluorescence.
    C3 protein fragments deposited on kidney cells of MPL-lpr mouse. Glomerular staining pattern.