Anti-Galectin 7 antibody

• 产品名称

  Anti-Galectin 7抗体
  参阅全部 Galectin 7 一抗

• 描述

  兔多克隆抗体to Galectin 7

• 宿主

  Rabbit

• 经测试应用

  适用于: WB, ICC/IF, IP, IHC-Pmore details

• 种属反应性

  与反应: Mouse, Human
  预测可用于: Chimpanzee, Gorilla, Orangutan

• 免疫原

  Synthetic peptide corresponding to Human Galectin 7 aa 100 to the C-terminus.
  Database link: 3963

• 常规说明

  
  

  The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

  
  

  The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

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• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

• 存储溶液

  pH: 7
  Preservative: 0.1% Sodium azide
  Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris

• 纯度

  Immunogen affinity purified

• 纯化说明

  Antibodies were affinity purified using the peptide immobilized on solid support.

• Primary antibody说明

  The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab10482于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

数据库链接

• Entrez Gene: 3963 Human

• Entrez Gene: 653499 Human

• Entrez Gene: 16858 Mouse

• Omim: 600615 Human

• SwissProt: P47929 Human

• SwissProt: O54974 Mouse

• Unigene: 558355 Human

• Unigene: 707031 Human

• Unigene: 20973 Mouse

别名

• Gal-7 antibody

• GAL7 antibody

• Galectin 7B antibody

• Galectin-7 antibody

• HKL-14 antibody

• Human keratinocyte lectin 14 antibody

• Keratinocyte lectin 14 antibody

• Lectin galactoside binding soluble 7 antibody

• Lectin, galactoside binding, soluble, 7B antibody

• LEG7_HUMAN antibody

• LGALS7 antibody

• LGALS7A antibody

• LGALS7B antibody

• P53 induced protein 1 antibody

• p53-induced gene 1 protein antibody

• Pi7 antibody

• PIG1 antibody

• TP53I1 antibody

• Western blot - Anti-Galectin 7 antibody (ab10482)

  ab10481 detection of mouse galectin 7 by Western blot and immunoprecipitation. Samples: A. Modified RIPA extract (10 µg) from the epidermis of FVB wild-type (wt) or galectin 7 transgenic (TG) mice. B. Modified RIPA extract (20 µg) from the epidermis of FVB wild-type mice. Antibody: ab10482 used at 0.005 (A) or 0.0025 (B) µg/ml for WB and as indicated for IP. Detection: Chemiluminescence with 1 second exposure time.

  ab10481 detection of mouse galectin 7 by Western blot and immunoprecipitation. Samples: A. Modified RIPA extract (10 µg) from the epidermis of FVB wild-type (wt) or galectin 7 transgenic (TG) mice. B. Modified RIPA extract (20 µg) from the epidermis of FVB wild-type mice. Antibody: ab10482 used at 0.005 (A) or 0.0025 (B) µg/ml for WB and as indicated for