Anti-TAGLN/Transgelin antibody

• 产品名称

  Anti-TAGLN/Transgelin抗体
  参阅全部 TAGLN/Transgelin 一抗

• 描述

  山羊多克隆抗体to TAGLN/Transgelin

• 宿主

  Goat

• 经测试应用

  适用于: WB, IHC-P, IHC-Fr, ICC/IF, IHC-FoFr, Flow Cytmore details

• 种属反应性

  与反应: Mouse, Rat, Rabbit, Human
  预测可用于: Cow, Dog

• 免疫原

  Synthetic peptide corresponding to Human TAGLN/Transgelin aa 189-200 (C terminal).
  Sequence:

  C-MTGYGRPRQIIS

  
  (Peptide available as ab16067, ab23184)

  Run BLAST with Run BLAST with 

• 阳性对照

• WB: Human testes lysate

• 常规说明

  In contrast to fast and slow skeletal muscle cells that fuse and terminally differentiate, smooth muscle cells are able to simultaneously proliferate and express lineage-restricted proteins. One of these proteins, expressed exclusively in smooth muscles, has been referred to as SM22-alpha, a 22-kD protein with structural similarity to the vertebrate thin filament myofibrillar regulatory protein calponin and the Drosophila muscle protein mp20, neither of which play a direct role in the contractile apparatus. The protein is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

  
  

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• 形式

  Liquid

• 存放说明

  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• 存储溶液

  pH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: Tris buffered saline, 0.5% BSA

• 浓度

• 100 µg 浓度为 0.5 mg/ml

• 纯度

  Immunogen affinity purified

• 纯化说明

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Primary antibody说明

  In contrast to fast and slow skeletal muscle cells that fuse and terminally differentiate, smooth muscle cells are able to simultaneously proliferate and express lineage-restricted proteins. One of these proteins, expressed exclusively in smooth muscles, has been referred to as SM22-alpha, a 22-kD protein with structural similarity to the vertebrate thin filament myofibrillar regulatory protein calponin and the Drosophila muscle protein mp20, neither of which play a direct role in the contractile apparatus. The protein is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

• 克隆

  多克隆

• 同种型

  IgG

The Abpromise guarantee

Abpromise™承诺保证使用ab10135于以下的经测试应用

“应用说明”部分 下显示的仅为推荐的起始稀释度；实际最佳的稀释度/浓度应由使用者检定。

数据库链接

• Entrez Gene: 6876 Human

• Entrez Gene: 21345 Mouse

• Entrez Gene: 25123 Rat

• SwissProt: Q01995 Human

• SwissProt: P37804 Mouse

• SwissProt: P31232 Rat

• Unigene: 410977 Human

• Unigene: 283283 Mouse

• Unigene: 34397 Rat

别名

• 22 kDa actin-binding protein antibody

• Protein WS3-10 antibody

• SM22 antibody

• SM22-alpha antibody

• Smooth muscle protein 22-alpha antibody

• TAGL_HUMAN antibody

• TAGLN antibody

• Transgelin antibody

• WS3-10 antibody

图片

• 

  Western blot - Anti-TAGLN/Transgelin antibody (ab10135)

  Anti-TAGLN/Transgelin antibody (ab10135) at 0.3 µg/ml + Human Testes lysate at 35 µg
  
  Predicted band size: 23 kDa