Pancreas specific protein disulfide isomerase antibody Pancreas-specific protein disulfide isomerase antibody Pancreatic protein disulfide isomerase antibody PDA2 antibody PDI antibody PDIA2 antibody PDIA2_HUMAN antibody PDIp antibody PDIR antibody Protein disulfide isomerase A2 antibody Protein disulfide isomerase antibody Protein disulfide isomerase associated 2 antibody Protein disulfide isomerase family A member 2 antibody Protein disulfide isomerase pancreatic antibody Protein disulfide-isomerase A2 antibody Rho GDP dissociation inhibitor gamma antibody
Product description
Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WBFC
WB:1:1,000-1:2,000 FC:1:50-1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
Pancreas specific protein disulfide isomerase antibody Pancreas-specific protein disulfide isomerase antibody Pancreatic protein disulfide isomerase antibody PDA2 antibody PDI antibody PDIA2 antibody PDIA2_HUMAN antibody PDIp antibody PDIR antibody Protein disulfide isomerase A2 antibody Protein disulfide isomerase antibody Protein disulfide isomerase associated 2 antibody Protein disulfide isomerase family A member 2 antibody Protein disulfide isomerase pancreatic antibody Protein disulfide-isomerase A2 antibody Rho GDP dissociation inhibitor gamma antibody
Fig1: Western blot analysis of PDI on different lysates using anti-PDI antibody at 1/1,000 dilution. Positive control: Lane 1: NIH/3T3 Lane 2: Human liver
Application
Fig2: Flow cytometric analysis of Hela cells with PDI antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody
Positive Control
NIH/3T3, human liver tissue.
Application Notes
WB:1:1,000-1:2,000 FC:1:50-1:100
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
