NAD dependent deacetylase sirtuin 5 antibody NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody NAD dependent protein deacylase sirtuin 5 mitochondrial antibody NAD-dependent protein deacylase sirtuin-5, mitochondrial antibody Regulatory protein SIR2 homolog 5 antibody Silent mating type information regulation 2 S.cerevisiae homolog 5 antibody Sir2 like 5 antibody SIR2-like protein 5 antibody SIR2L5 antibody SIR5_HUMAN antibody Sirt5 antibody Sirtuin 5 antibody Sirtuin type 5 antibody
Product description
SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Immunogen
recombinant protein
Key Feature
Clonality
Monoclonal
Isotype
IgG
Host Species
Recombinant rabbit
Tested Applications
WB
WB:1:1,000-1:2,000
Species Reactivity
HumanMouse
Concentration
1mg/ml
Target Information
Alternative Names
NAD dependent deacetylase sirtuin 5 antibody NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody NAD dependent protein deacylase sirtuin 5 mitochondrial antibody NAD-dependent protein deacylase sirtuin-5 mitochondrial antibody Regulatory protein SIR2 homolog 5 antibody Silent mating type information regulation 2 S.cerevisiae homolog 5 antibody Sir2 like 5 antibody SIR2-like protein 5 antibody SIR2L5 antibody SIR5_HUMAN antibody Sirt5 antibody Sirtuin 5 antibody Sirtuin type 5 antibody
