AGM6 antibody B cell antigen receptor complex associated protein beta chain antibody B cell specific glycoprotein B29 antibody B-cell antigen receptor complex-associated protein beta chain antibody B-cell-specific glycoprotein B29 antibody B29 antibody B29/Ig-beta/CD79b antibody CD 79b antibody CD79b antibody CD79b antigen (immunoglobulin associated beta) antibody CD79b antigen antibody CD79b molecule antibody CD79b molecule immunoglobulin associated beta antibody CD79b protein antibody CD79B_HUMAN antibody Ig beta antibody Ig-beta antibody IGB antibody Igbeta antibody Immunoglobulin associated B29 antibody Immunoglobulin associated B29 protein antibody Immunoglobulin associated beta antibody Immunoglobulin associated protein antibody Immunoglobulin-associated B29 protein antibody MGC108607 antibody
Product description
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Immunogen
Purified recombinant fragment of human CD79B (AA: extra 30-160) expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Host Species
Mouse
Tested Applications
WB
WB:1:500-1:2,000
Species Reactivity
Human
Concentration
1mg/mL
Target Information
Alternative Names
AGM6 antibody B cell antigen receptor complex associated protein beta chain antibody B cell specific glycoprotein B29 antibody B-cell antigen receptor complex-associated protein beta chain antibody B-cell-specific glycoprotein B29 antibody B29 antibody B29/Ig-beta/CD79b antibody CD 79b antibody CD79b antibody CD79b antigen (immunoglobulin associated beta) antibody CD79b antigen antibody CD79b molecule antibody CD79b molecule immunoglobulin associated beta antibody CD79b protein antibody CD79B_HUMAN antibody Ig beta antibody Ig-beta antibody IGB antibody Igbeta antibody Immunoglobulin associated B29 antibody Immunoglobulin associated B29 protein antibody Immunoglobulin associated beta antibody Immunoglobulin associated protein antibody Immunoglobulin-associated B29 protein antibody MGC108607 antibody
Molecular Weight(MW)
26kDa
Cellular Localization
Cell membrane. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Western blot analysis of CD79B against human CD79B (AA: extra 30-160) recombinant protein. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1710-96, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.
Application
Western blot analysis of EM1710-96 against HEK293 (1) and CD79B (AA: extra 30-160)-hIgGFc transfected HEK293 (2) cell lysate.Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (EM1710-96, 1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Mouse IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature.
Positive Control
B-cells.
Application Notes
WB:1:500-1:2,000
Additional Information
Form
Liquid
Storage Instructions
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
