| 存储条件 |
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| Product Name | BMPR2 [F8-G6] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMP type II receptor antibody BMP type-2 receptor antibody BMPR 2 antibody BMPR 3 antibody BMPR II antibody BMPR-2 antibody BMPR-II antibody Bmpr2 antibody BMPR2_HUMAN antibody BMPR3 antibody BMPRII antibody BMR 2 antibody BMR2 antibody Bone morphogenetic protein receptor type 2 antibody Bone morphogenetic protein receptor type II antibody Bone morphogenetic protein receptor type-2 antibody Bone morphogenic protein receptor type II serine threonine kinase antibody BRK 3 antibody BRK3 antibody PPH 1 antibody PPH1 antibody Serine threonine kinase type II activin receptor like kinase antibody T ALK antibody TALK antibody Type II activin receptor like kinase antibody |
| Product description | Members of the transforming growth factor βsuperfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex. Two type I receptors have been characterized, BMPR-IA (also designated SKR5, ALK-3, and BRK-1) and BMPR-IB (also designated ALK-6 and SKR 6), that bind to bone morphogenetic proteins (BMP)-2, BMP-4, and osteogenic protein (OP)-1 (also designated BMP-7). BMPR-IA and BMPR-IB are both expressed in human glioma cell lines. The type II receptor, BMPR-II, efficiently binds to OP-1 and BMP-2 and weakly binds BMP-4, and it is widely expressed in different tissues, including brain (1,5,6). The BMP receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morphogenesis in a dose dependent fashion. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 | |
| Species Reactivity | HumanMouseRatMonkey |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | BMP type II receptor antibody BMP type-2 receptor antibody BMPR 2 antibody BMPR 3 antibody BMPR II antibody BMPR-2 antibody BMPR-II antibody Bmpr2 antibody BMPR2_HUMAN antibody BMPR3 antibody BMPRII antibody BMR 2 antibody BMR2 antibody Bone morphogenetic protein receptor type 2 antibody Bone morphogenetic protein receptor type II antibody Bone morphogenetic protein receptor type-2 antibody Bone morphogenic protein receptor type II serine threonine kinase antibody BRK 3 antibody BRK3 antibody PPH 1 antibody PPH1 antibody Serine threonine kinase type II activin receptor like kinase antibody T ALK antibody TALK antibody Type II activin receptor like kinase antibody |
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| Molecular Weight(MW) | 115 kDa |
| Cellular Localization | Membrane. |
| SwissProt ID | Q13873 |
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Application
Application
Application
Fig2: ICC staining BMPR2 (green) and actin filaments (red) in Eca109 cellS. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded muscle tissue using anti-BMPR2 antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded kidney cancer tissues using anti-BMPR2 antibody. Counter stained with hematoxylin.| Positive Control | Hela, NIH/3T3, A431, PC-12, Cos7, muscle tissue, kidney cancer tissue, Eca109. |
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| Application Notes | WB:1:500-1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 |
| Form | Liquid |
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| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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