| 存储条件 |
|---|
| Product Name | LPA [B6-H1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AK38 antibody Antiangiogenic AK38 protein antibody apo(a) antibody APOA antibody apolipoprotein(a) antibody LP antibody lp(a) antibody LPA antibody |
| Product description | The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. |
| Immunogen | Recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 | |
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Purification | Unpurified |
| Alternative Names | AK38 antibody Antiangiogenic AK38 protein antibody apo(a) antibody APOA antibody apolipoprotein(a) antibody LP antibody lp(a) antibody LPA antibody |
|---|---|
| Molecular Weight(MW) | 501 kDa |
| Cellular Localization | Extracellular region. Secreted. |
| SwissProt ID | P08519 |
|---|
Application
Fig1: Western blot analysis of Lipoprotein a on human Lipoprotein a recombinant protein using anti- Lipoprotein a antibody at 1/1,000 dilution.
Application
Fig2: ICC staining Lipoprotein a (green) and actin filaments (red) in HepG2 cell. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
Application
Fig4: Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.
Application
Fig5: Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti- Lipoprotein a antibody. Counter stained with hematoxylin.| Positive Control | Human Lipoprotein a recombinant protein, HepG2, human liver cancer tissue, human breast cancer tissue, human rectum cancer tissue. |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:50-1:200 IHC:1:50-1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
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